<i>In vitro</i> Release Kinetic Study of Esomeprazole Magnesium from Methocel K15M and Methocel K100 LVCR Matrix Tablets
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چکیده
منابع مشابه
Development and Evaluation of Sustained Release Matrix Tablets of Indapamide using Methocel K15M CR
Article history: Received on: 07/04/2013 Revised on: 29/04/2013 Accepted on: 14/05/2013 Available online: 30/05/2013 In the present study an attempt has been taken to develop Indapamide sustained release matrix tablet using Methocel K15M CR by direct compression method. Various amount of polymer was used in the five proposed formulations (F-1to F-5) for the study of release rate retardant effec...
متن کاملDesign and In-vitro Evaluation of Indapamide Sustained Release Tablet Using Methocel K15 Mcr and Methocel K100m Lvcr
Indapamide, a low-dose thiazide-type diuretic, is used for the treatment of essential hypertension. In this study, we developed an indapamide sustained release formulation using Methocel K15M CR and Methocel K100M LVCR, starch 1500, talc and magnesium stearate considering technical feasibility and performed a comparative study with the release pattern. The tablets showed sustained release curve...
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The purpose of the present investigation was to design and evaluate sustained release tablets of a poorly water soluble drug nifedipine, employing hydrophilic polymers Methocel K15M CR and Methocel K100LV CR and to select the best formulation based on pharmacokinetic studies. Direct compression method was used to prepare matrix tablets. The granules were evaluated for angle of repose, loose bul...
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In present study an attempt was made to formulate and to evaluate the sustain release Carvedilol matrix tablets by using METHOCEL K100LV CR, METHOCEL K100M CR and Xanthum Gum polymer. The tablets were prepared by direct compression method. The granules were evaluated by angle of repose, bulk density, tapped density and compressibility index, surface P. The formulated tablets were evaluated by w...
متن کاملFormulation and In-Vitro Evaluation of Controlled Release Matrix Tablets of Diltiazem Hydrochloride Using Different Rate Controlling Polymers
In present study, directly compressed controlled released matrix tablets of Diltiazem Hydrochloride were formulated at drug-to-polymer ratios (D: P) of 10:1, 10:2, 10:3 using polymers Ethocel 45 Premium, K100 LV Methocel, K15M EP Premium Methocel as rate controlling agents. In some formulations of Diltiazem hydrochloride and Ethocel 45 Premium matrices, 30% of filler was replaced by Co-excipien...
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ژورنال
عنوان ژورنال: Dhaka University Journal of Pharmaceutical Sciences
سال: 1970
ISSN: 1816-1839,1816-1820
DOI: 10.3329/dujps.v7i1.1216